Medical application of ICG near-infrared fluorescence imaging technology

In addition to endoscopic surgery navigation, ICG near-infrared fluorescence imaging technology can also be applied to the following medical products and fields:

1. Tumor imaging and localization.

ICG can specifically accumulate in tumor tissues. Near-infrared imaging systems can clearly image the location, size and shape of tumors to provide accurate positioning references for surgical resection.

2. Hemodynamic detection.

ICG in the blood circulation can be quickly absorbed and cleared. It can be used to detect cardiac output, hepatic blood flow and renal blood flow, to achieve non-invasive dynamic monitoring.

3. Physiological function evaluation.

ICG can be used to evaluate liver function and kidney function. Due to its high correlation with organ function, ICG distribution and clearance in the body can be quantitatively analyzed to evaluate the physiological functions of target organs.

4. Drug delivery and efficacy evaluation.

ICG can be combined with certain drugs for carriage to study the absorption, distribution and metabolism of drugs in the body, providing a basis for new drug research and development. This can also be used to evaluate the effectiveness and delivery of cancer therapies.

5. Minimally invasive surgical devices.

Near-infrared imaging navigation systems can be integrated into robotic surgical systems, natural orifice transluminal endoscopic surgery (NOTES) and other minimally invasive surgical platforms to provide support for precise intraoperative positioning, blood vessel identification and functional evaluation.

6. Contrast agent research and development.

The fluorescent properties of ICG make it an ideal model and reference standard for the research and development of contrast agents. New contrast agents are usually evaluated for efficacy and safety against ICG as a control group during the R&D process.

In addition, ICG also shows great potential in newborn monitoring, brain death determination, tissue congestion detection and other fields. With the improvement of ICG production technology and imaging equipment, its medical applications will continue to expand.