How photodynamic diagnosis of PDD autofluorescence is applied in the medical field

Photodynamic diagnosis (PDD) is a non-invasive treatment method that uses photosensitive drugs and specific wavelengths of light to kill target cells. It can be used to treat various tumors and other diseases. The main applications of PDD include:

1. Tumor treatment.

PDD can be used to treat solid tumors such as lung cancer, esophageal cancer, gastric cancer, breast cancer, prostate cancer, glioblastoma, etc. By intravenous injection of fluorescent drugs and then laser irradiation of the tumor, tumor cells can be induced to produce oxidative stress and necrosis.

2. Skin disease treatment.

PDD can be used to treat skin lesions such as squamous cell carcinoma, basal cell carcinoma, and hair follicle tumors. By topical or local injection of fluorescent drugs and then light irradiation, diseased cells can be selectively damaged.

3. Vascular disease treatment.

PDD can be used to treat varicose veins, spider angiomas and other vascular diseases. By intravenous injection of fluorescent drugs and then laser irradiation of the diseased blood vessels, vascular occlusion and atrophy can be induced.

4. Infection treatment.

Some fluorescent drugs can accumulate on pathogens such as bacteria and viruses. PDD can be used to treat infectious diseases in areas such as abscesses, liver abscesses, and genital tract infections.

5. Diagnostic applications.

Some fluorescent drugs can specifically accumulate in diseased tissues or microorganisms. Fluorescence imaging systems can clearly show the location, size, shape, etc. of the lesions to achieve accurate positioning and diagnosis of the lesions. This provides strong support for minimally invasive treatment and surgical treatment.

In summary, the application of PDD in hospitals is very extensive. It can not only be used to treat various solid tumors, skin diseases, vascular diseases and infections, but also achieve accurate diagnosis and positioning of lesions. With the continuous improvement of photosensitive drugs and light source devices, the range and effect of PDD treatment will be further improved.